Description

2'-o-Monosuccinyladenosine 3':5'-Cyclic Monophosphate is a chemically modified derivative of cyclic adenosine monophosphate (cAMP), a fundamental secondary messenger in cellular signaling. This succinylated analog is specifically engineered to enhance membrane permeability and stability, making it a critical tool for modulating intracellular cAMP-dependent pathways in research. It is primarily utilized by pharmaceutical researchers, biochemical manufacturers, and academic institutions engaged in advanced studies of signal transduction, enzyme regulation, and drug discovery.

Application

• Biochemical Research: A key reagent for studying cAMP-dependent protein kinase (PKA) activation and other intracellular signaling cascades.
• Pharmaceutical Development: Used as a reference standard or an active intermediate in the development of novel therapeutics targeting metabolic and cardiovascular diseases.
• Cell Biology Studies: Employed to investigate the role of cAMP in cellular processes such as gene expression, ion channel function, and metabolism.
• Enzyme Assays: Serves as a substrate or modulator in enzymatic assays to study phosphodiesterase (PDE) activity and inhibition.
• Diagnostic Kit Manufacturing: May be incorporated as a component in high-sensitivity immunoassays and diagnostic kits for research purposes.

Basic Information

Product Name	2'-o-Monosuccinyladenosine 3':5'-Cyclic Monophosphate
CAS No.	36940-87-1
Molecular Formula	C19H22N5O11P
Molecular Weight	527.38 g/mol
Synonyms	2'-O-Succinyl-cAMP; N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt (common mis-association); Adenosine 3',5'-cyclic monophosphate, 2'-O-monosuccinyl; 2'-O-(Monosuccinyl)adenosine-3',5'-cyclic monophosphate; Succinyl-cAMP; cAMP 2'-O-succinate; 2'-O-Succinyladenosine cyclic 3',5'-(hydrogen phosphate)
EINECS	Contact for details

Quality Control

Our 2'-o-Monosuccinyladenosine 3':5'-Cyclic Monophosphate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Custom synthesis and purification to meet specific project requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.