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5-Methoxyuridine-5'-Monophosphate CAS NO 36908-07-3


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CAS No.:36908-07-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Methoxyuridine-5'-Monophosphate is a modified nucleoside monophosphate, a key building block in nucleic acid chemistry and biochemical research. This compound is valued for its role in the synthesis of oligonucleotides with specific modifications, enabling advanced studies in molecular biology, virology, and drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

  • Oligonucleotide Synthesis: A crucial phosphoramidite precursor for the solid-phase synthesis of modified DNA and RNA strands.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleic acid metabolism and related pathways.
  • Antiviral Drug Development: Serves as a key intermediate in the research and development of nucleoside analog-based antiviral therapeutics.
  • Diagnostic Probe Design: Incorporated into nucleic acid probes to enhance stability, specificity, or detection capabilities in diagnostic assays.
  • Enzyme Mechanism Studies: Employed to study the structure and function of polymerases, kinases, and other nucleic acid-processing enzymes.
  • Labeling and Tracing: Can be used in the preparation of radiolabeled or fluorescently tagged nucleotides for tracking and imaging studies.

Basic Information

Product Name 5-Methoxyuridine-5'-Monophosphate
CAS No. 36908-07-3
Molecular Formula C10H15N2O10P
Molecular Weight 354.21 g/mol
Synonyms 5-Methoxy-UMP; 5-Methoxyuridylic acid; 5-Methoxyuridine 5'-(dihydrogen phosphate); 5-Methoxy-1-β-D-ribofuranosyluracil 5'-monophosphate; 5-OMe-UMP; 5-Methoxyuridine monophosphate; p5MethoxyU
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Quality Control

Our 5-Methoxyuridine-5'-Monophosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide Certificates of Analysis (COA) with detailed specifications for identity, purity, and impurity profiles to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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