Description

2-Isothiocyanatomethyl-Thiophene is a specialized heterocyclic building block featuring both a thiophene ring and a reactive isothiocyanate functional group. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and agrochemical development. It is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its reactive site for structural diversification.
• Material Science Research: Serves as a precursor for functional polymers or organic electronic materials due to the presence of the thiophene moiety.
• Chemical Biology Probes: The isothiocyanate group allows for covalent conjugation to biomolecules, useful in creating probes for biochemical assays.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	2-Isothiocyanatomethyl-Thiophene
CAS No.	36810-92-1
Molecular Formula	C6H5NS2
Molecular Weight	155.24 g/mol
Synonyms	2-(Isothiocyanatomethyl)thiophene; Thiophene-2-methylene isothiocyanate; 2-Thienylmethyl isothiocyanate; (Thiophen-2-ylmethyl) isothiocyanate; Isothiocyanic acid, (2-thienylmethyl) ester; 2-Thiophenemethyl isothiocyanate; NSC 163490; AI3-52095
EINECS	Contact for details

Quality Control

Our 2-Isothiocyanatomethyl-Thiophene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.