Description

3-Picolyl Isothiocyanate Hydrobromide is a versatile organosulfur building block and reagent of significant interest in synthetic organic and medicinal chemistry. Its core value lies in its bifunctional structure, combining a reactive isothiocyanate group with a pyridine moiety, which facilitates its use in the synthesis of complex heterocycles and functionalized molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in developing novel therapeutic agents, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly those targeting enzyme inhibition or requiring specific heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive sites to create bioactive molecules.
• Chemical Biology Probe Development: Serves as a reagent for modifying proteins or other biomolecules, useful in studying biological pathways and target engagement.
• Ligand and Catalyst Precursor: Employed in the preparation of specialized ligands for metal complexes used in catalysis or material science.
• Heterocyclic Compound Library Synthesis: A valuable reactant for generating diverse libraries of nitrogen and sulfur-containing heterocycles for high-throughput screening.
• Research & Development (R&D): Fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	3-Picolyl Isothiocyanate Hydrobromide
CAS No.	36810-90-9
Molecular Formula	C7H7N2S·HBr
Molecular Weight	231.12 g/mol
Synonyms	3-Pyridylmethyl Isothiocyanate Hydrobromide; (Pyridin-3-ylmethyl) Isothiocyanate Hydrobromide; 3-(Isothiocyanatomethyl)pyridine Hydrobromide; 3-PICIT HBr; 3-Pyridinemethanamine, N-(thiocarbonyl)-, hydrobromide; 3-Picolylamine, N-thiocarbonyl-, hydrobromide
EINECS	Contact for details

Quality Control

Our 3-Picolyl Isothiocyanate Hydrobromide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.