Description

2-Tetrahydrofurfuryl Isothiocyanate is a versatile heterocyclic organic compound featuring both a tetrahydrofuran ring and a reactive isothiocyanate functional group. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of novel chemical entities. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Chemical Research Reagent: Employed in academic and industrial laboratories for studying cycloaddition reactions, nucleophilic additions, and as a linker in heterocyclic chemistry.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialized polymers and resins with tailored properties.
• Bioconjugation Chemistry: The reactive isothiocyanate group can be used to modify proteins, peptides, or other biomolecules for labeling and probe development.

Basic Information

Product Name	2-Tetrahydrofurfuryl Isothiocyanate
CAS No.	36810-87-4
Molecular Formula	C6H9NOS
Molecular Weight	143.21 g/mol
Synonyms	2-(Isothiocyanatomethyl)tetrahydrofuran; Tetrahydrofurfuryl Isothiocyanate; 2-THF Isothiocyanate; (Tetrahydrofuran-2-yl)methyl Isothiocyanate; 2-(Isothiocyanatomethyl)oxolane; 2-THF-NCS; NCS-THF-CH2; (Oxolan-2-yl)methyl Isothiocyanate
EINECS	Contact for details

Quality Control

Every batch of 2-Tetrahydrofurfuryl Isothiocyanate is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through comprehensive analytical protocols including HPLC, GC, and NMR. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.