Description

8-Methylguanosine is a modified nucleoside derivative of guanosine, featuring a methyl group at the 8-position of the purine ring. This structural modification makes it a valuable biochemical tool and a key intermediate in the research of nucleic acid chemistry and metabolism. It is primarily utilized in life science research, pharmaceutical development, and as a reference standard. The compound is supplied to meet the stringent requirements of research and industrial applications where precise chemical structure and high purity are critical.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to RNA modification and processing.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel nucleoside-based therapeutics and antiviral agents.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and metabolic studies.
• Nucleic Acid Chemistry: Acts as a modified monomer for studying the structure, function, and stability of RNA molecules.
• Diagnostic Reagent Development: Utilized in the formulation of kits and assays for detecting specific enzymes or metabolic pathways.

Basic Information

Product Name	8-Methylguanosine
CAS No.	36799-17-4
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	8-Methylguanosine; Guanosine, 8-methyl-; 8-Methyl-9H-purin-6-amine, 9-β-D-ribofuranosyl-; 8-Methyl-G; 8-MeG; 8-Methylguanosine riboside; 8-Methylguanine riboside; 8-Methylguanosine (nucleoside)
EINECS	Contact for details

Quality Control

Our 8-Methylguanosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-grade specifications suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.