Description

3-Isothiazolecarbonylchloride,5-Nitro-(9Ci) CAS NO 36778-14-0 is a specialized heterocyclic building block and reactive intermediate of significant interest in advanced organic synthesis. Its core value lies in the presence of both a highly reactive acid chloride group and a nitro-substituted isothiazole ring, enabling precise molecular construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Research: Serves as a precursor for functional polymers or ligands with specific electronic or binding properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	3-Isothiazolecarbonylchloride,5-Nitro-(9Ci)
CAS No.	36778-14-0
Molecular Formula	C4H2ClN2O3S
Molecular Weight	193.59 g/mol
Synonyms	5-Nitroisothiazole-3-carbonyl chloride; 5-Nitro-1,2-thiazole-3-carbonyl chloride; 3-Carbonylchloride-5-nitroisothiazole; 5-Nitro-3-isothiazolecarbonyl chloride; 5-Nitroisothiazole-3-carboxylic acid chloride; 36778-14-0; 5-Nitro-1,2-thiazole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Isothiazolecarbonylchloride,5-Nitro-(9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.