Description

3β-Acetyloxy-14,15β-Epoxy-16-Oxo-5β-Bufa-20,22-Dienolide is a high-purity, specialized bufadienolide derivative, a class of compounds known for their potent biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycoside analogs and other bioactive molecules.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical and research settings.
• Biochemical Research: Employed in studies investigating Na+/K+-ATPase inhibition, cell signaling pathways, and structure-activity relationships (SAR).
• Preclinical Studies: Serves as a starting material or a comparative compound in pharmacological and toxicological research.
• Fine Chemical Synthesis: Utilized in the preparation of complex, high-value organic molecules for specialized applications.

Basic Information

Product Name	3β-Acetyloxy-14,15β-Epoxy-16-Oxo-5β-Bufa-20,22-Dienolide
CAS No.	36615-16-4
Molecular Formula	C₂₆H₃₂O₇
Molecular Weight	456.53 g/mol
Synonyms	3β-Acetoxy-14β,15β-epoxy-5β-bufa-20,22-dienolide-16-one; 3β-Acetoxy-14,15-epoxy-16-oxo-5β-bufa-20,22-dienolide; 14,15-Epoxy-3β-hydroxy-16-oxobufa-20,22-dienolide 3-acetate; Bufadienolide derivative; 3β-Acetyloxy-14,15β-epoxy-16-oxo-5β-bufa-20,22-dienolide; 16-Oxobufalin 3-acetate 14,15-epoxide
EINECS	Contact for details

Quality Control

Our 3β-Acetyloxy-14,15β-Epoxy-16-Oxo-5β-Bufa-20,22-Dienolide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR, MS), to ensure it meets stringent specifications for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be handled in accordance with good laboratory practices to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.