Description

2-Aminopurine Ribodylic Acid is a modified nucleoside analog of significant interest in biochemical and pharmaceutical research. Its core value lies in its utility as a fluorescent probe and a building block for oligonucleotide synthesis, enabling advanced studies in molecular biology and drug discovery. This compound is essential for researchers and manufacturers in the fields of nucleic acid chemistry, diagnostic assay development, and antiviral/anticancer research.

Application

• Fluorescent Labeling and Probes: Used as a site-specific fluorescent marker in oligonucleotides to study DNA/RNA structure, dynamics, and protein-nucleic acid interactions.
• Oligonucleotide Synthesis: Serves as a modified phosphoramidite or solid-support reagent for the automated synthesis of probe sequences.
• Biochemical Research: A critical tool for investigating mutagenesis, polymerase fidelity, and the mechanisms of nucleic acid enzymes.
• Diagnostic Development: Incorporated into molecular beacon probes and other assay systems for the detection of specific genetic sequences.
• Pharmaceutical R&D: Explored as a precursor or analog in the development of nucleoside-based antiviral and anticancer agents.
• Academic Research: Fundamental studies in biophysics and chemical biology to understand base-pairing and nucleic acid fluorescence.

Basic Information

Product Name	2-Aminopurine Ribodylic Acid
CAS No.	36475-53-3
Molecular Formula	C10H14N5O7P
Molecular Weight	347.23 g/mol
Synonyms	2-Aminopurine Ribonucleotide; 2-Aminopurine Riboside 5'-Monophosphate; 2-APRMP; 2-Aminopurine-9-β-D-ribofuranoside 5'-monophosphate; 9-β-D-Ribofuranosyl-2-aminopurine 5'-monophosphate; 2-AP Ribonucleotide; 2-Aminopurine-9-β-D-riboside 5'-phosphate
EINECS	Contact for details

Quality Control

Our 2-Aminopurine Ribodylic Acid is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.