Description

5-Methyl-2-Phenyl-2H-1,2,3-Triazole-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key acylating agent for introducing the 1,2,3-triazole-4-carbonyl moiety into target molecules, enabling the development of novel compounds with specific functionalities. This product is critically needed by research and development laboratories, pharmaceutical companies, and agrochemical manufacturers focused on creating new active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other bioactive molecules containing the 1,2,3-triazole scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the triazole ring contributes to biological activity.
• Material Science Research: Serves as a precursor for creating functional polymers, ligands for metal-organic frameworks (MOFs), and other advanced materials with tailored properties.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity tags for studying protein function and interactions.
• Dye & Pigment Industry: Acts as an intermediate in the synthesis of specialized heterocyclic dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke compounds for clients.

Basic Information

Product Name	5-Methyl-2-Phenyl-2H-1,2,3-Triazole-4-Carbonyl Chloride
CAS No.	36401-55-5
Molecular Formula	C10H8ClN3O
Molecular Weight	221.64 g/mol
Synonyms	5-Methyl-2-phenyl-2H-1,2,3-triazole-4-carbonyl chloride; 1,2,3-Triazole-4-carbonyl chloride, 5-methyl-2-phenyl-; 4-Carbonyl chloride-5-methyl-2-phenyl-1,2,3-triazole; 2-Phenyl-5-methyl-2H-1,2,3-triazole-4-carbonyl chloride; 5-Methyl-2-phenyl-1,2,3-triazole-4-carboxylic acid chloride; 36401-55-5 (CAS); MPTC-Cl
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Phenyl-2H-1,2,3-Triazole-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.