Description

N6-Cyclohexyladenosine is a potent and selective adenosine A1 receptor agonist, a key compound for modulating adenosine signaling pathways in biological research. This high-purity chemical is essential for investigating cardiovascular, neurological, and renal functions, as well as for developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic researchers in pharmacology and biochemistry, and manufacturers of high-value fine chemicals for advanced life science applications.

Application

• Pharmacological Research: A critical tool for studying adenosine A1 receptor-mediated effects in cardiovascular protection, neuroprotection, and anti-nociception.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in the design of new A1 receptor-targeting therapeutics for conditions like cardiac arrhythmias and neuropathic pain.
• Biochemical Assays: Used in in vitro and in vivo studies to elucidate the role of adenosine signaling in metabolic regulation and ischemia-reperfusion injury.
• Neuroscience Studies: Employed to investigate synaptic transmission, neuronal excitability, and the potential for treating seizures and neurodegenerative diseases.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: An advanced intermediate for the synthesis of more complex adenosine receptor modulators and labeled analogs for tracer studies.

Basic Information

Product Name	N6-Cyclohexyladenosine
CAS No.	36396-99-3
Molecular Formula	C16H23N5O4
Molecular Weight	349.39 g/mol
Synonyms	CHA; N6-Cyclohexyl-adenosine; Adenosine, N6-cyclohexyl-; Cyclohexyladenosine; N(6)-Cyclohexyladenosine; 2-Chloroadenosine; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide cyclohexyl derivative; N6-Cyclohexyl-9-β-D-ribofuranosyladenine
EINECS	Contact for details

Quality Control

Every batch of N6-Cyclohexyladenosine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for active pharmaceutical ingredients (APIs) and fine chemicals, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.