Description

n-Hydroxy-4-Methylbenzimidoyl Chloride is a versatile and reactive chemical intermediate of significant importance in advanced organic synthesis. Its core value proposition lies in its bifunctional nature, serving as a key building block for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of benzimidazole-based drug candidates, including potential antivirals, antifungals, and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel fungicides and herbicides, leveraging its reactive chloride and hydroxy groups for molecular diversification.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Employed in the synthesis of functional monomers and polymers with specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new reaction pathways and constructing complex molecular architectures.
• Dye and Pigment Intermediate: Utilized in the production of specialized colorants and imaging agents.

Basic Information

Product Name	n-Hydroxy-4-Methylbenzimidoyl Chloride
CAS No.	36288-37-6
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	N-Hydroxy-4-methylbenzenecarboximidoyl chloride; 4-Methyl-N-hydroxybenzimidoyl chloride; (4-Methylphenyl)(hydroxyimino)methane chloride; p-Tolyl(hydroxyimino)methane chloride; Hydroxy(4-methylphenyl)methanimidoyl chloride; Benzimidoyl chloride, N-hydroxy-4-methyl-; 4-Methylbenzhydroxamoyl chloride
EINECS	Contact for details

Quality Control

Our n-Hydroxy-4-Methylbenzimidoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' needs for reliable and traceable raw materials in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.