Description

trans-1,4-Cyclohexanedicarboxylic Acid Monomethyl Ester Chloride is a high-purity, versatile chemical intermediate characterized by its reactive acid chloride functionality. This compound is critical for introducing the rigid, lipophilic trans-1,4-cyclohexane moiety into target molecules, enabling the synthesis of advanced materials and fine chemicals. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring precise molecular architecture and enhanced stability.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring a rigid, saturated cyclohexane backbone to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the trans-cyclohexane structure contributes to efficacy and environmental persistence.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the synthesis of high-performance polyesters, polyamides, and liquid crystalline polymers, imparting thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in peptide coupling reactions and esterifications under mild conditions, facilitating the efficient construction of complex organic molecules in research and development.
• Liquid Crystal & OLED Materials: A precursor for dielectric and charge-transport materials used in display technologies and organic light-emitting diodes (OLEDs).
• Cosmetic & Fragrance Ingredient Synthesis: Used to create novel esters and other derivatives that serve as fixatives or active components in high-end cosmetic formulations.

Basic Information

Product Name	trans-1,4-Cyclohexanedicarboxylic Acid Monomethyl Ester Chloride
CAS No.	36218-60-7
Molecular Formula	C10H15ClO4
Molecular Weight	234.68 g/mol
Synonyms	trans-1,4-Cyclohexanedicarboxylic Acid Monomethyl Ester Acid Chloride; Methyl Hydrogen trans-1,4-Cyclohexanedicarboxylate Chloride; trans-Hexahydroterephthalic Acid Monomethyl Ester Chloride; 4-(Methoxycarbonyl)cyclohexanecarbonyl Chloride (trans); Monomethyl trans-Cyclohexane-1,4-dicarboxylate Chloride; trans-CHDM Monomethyl Ester Chloride; 1,4-CHDA Monomethyl Ester Chloride (trans)
EINECS	Contact for details

Quality Control

Our trans-1,4-Cyclohexanedicarboxylic Acid Monomethyl Ester Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and titration methods, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.