Description

14,16β-Dihydroxy-3,19-Dioxo-5α,14β-Bufa-20,22-Dienolide is a high-purity bufadienolide derivative, a specialized class of steroid-like compounds with significant biological activity. This compound is valued for its role as a critical pharmaceutical intermediate and reference standard in advanced research and development. It is primarily sought by pharmaceutical manufacturers and biochemical research institutions for the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardioactive or anticancer drug candidates.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate cellular signaling pathways and ion channel modulation.
• Reference Material: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Natural Product Chemistry: Used in the study and semi-synthesis of complex natural products derived from toad venom or related sources.
• Academic Research: Employed in universities and research institutes for studying the structure-activity relationships (SAR) of bufadienolides.

Basic Information

Item	Details
Product Name	14,16β-Dihydroxy-3,19-Dioxo-5α,14β-Bufa-20,22-Dienolide
CAS No.	36155-63-2
Molecular Formula	C₂₄H₃₂O₆
Molecular Weight	416.51 g/mol
Synonyms	14,16β-Dihydroxy-3,19-dioxo-5α,14β-bufa-20,22-dienolide; Bufadienolide derivative; 5α,14β-Bufa-20,22-dienolide-3,19-dione, 14,16β-dihydroxy-; 3,19-Dioxo-14,16β-dihydroxy-5α,14β-bufa-20,22-dienolide; 14,16β-Dihydroxybufa-20,22-dienolide-3,19-dione; (5α,14β)-14,16-Dihydroxy-3,19-dioxobufa-20,22-dienolide; 36155-63-2
EINECS	Contact for details

Quality Control

Our 14,16β-Dihydroxy-3,19-Dioxo-5α,14β-Bufa-20,22-Dienolide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a Certificate of Analysis (COA) with each shipment, detailing all relevant specifications to ensure it meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.