Description

3,4,5-Trimethoxyphenyl Isothiocyanate is a versatile and reactive organic building block characterized by its isothiocyanate functional group attached to a trimethoxyphenyl core. This compound is of significant value in synthetic organic chemistry for constructing complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for applications in medicinal chemistry, where it serves as a key precursor for the synthesis of potential drug candidates and bioactive heterocycles.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its reactive site for creating active ingredients.
• Chemical Biology Probe Development: Employed to create isothiocyanate-based probes for labeling and studying proteins and other biomolecules.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Academic & Industrial R&D: A fundamental reagent in organic synthesis laboratories for constructing complex molecular architectures.

Basic Information

Product Name	3,4,5-Trimethoxyphenyl Isothiocyanate
CAS No.	35967-24-9
Molecular Formula	C10H11NO3S
Molecular Weight	225.26 g/mol
Synonyms	1-Isothiocyanato-3,4,5-trimethoxybenzene; 3,4,5-Trimethoxybenzene Isothiocyanate; Gallic Acid Trimethyl Ether Isothiocyanate; 3,4,5-Trimethoxyphenyl Mustard Oil; NSC 403914; Trimethoxyphenyl Isothiocyanate; 3,4,5-TMP-ITC
EINECS	Contact for details

Quality Control

Our 3,4,5-Trimethoxyphenyl Isothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.