Description

2',5'-Dideoxyuridine is a modified nucleoside analog of significant interest in biochemical and pharmaceutical research. Its structural modification at the 2' and 5' positions of the ribose sugar makes it a valuable precursor and building block for the synthesis of more complex antiviral and anticancer nucleotide analogs. This compound is essential for researchers and manufacturers in the fields of medicinal chemistry and molecular biology who require high-purity intermediates for drug discovery and development programs.

Application

• Medicinal Chemistry Intermediate: A key synthetic precursor for the development of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used in studies investigating nucleoside metabolism, enzyme inhibition, and DNA/RNA synthesis pathways.
• Pharmaceutical Development: Serves as a critical starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs) for experimental therapies.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2',5'-Dideoxyuridine
CAS No.	35959-50-3
Molecular Formula	C9H12N2O4
Molecular Weight	212.20 g/mol
Synonyms	2',5'-Dideoxyuridine; 1-[(2R,5S)-5-(Hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 2',5'-ddU; 2',5'-Dideoxy-Uridine; Uridine, 2',5'-dideoxy-; 5-Methyl-2',5'-dideoxyuridine (related compound); DDU
EINECS	Contact for details

Quality Control

Our 2',5'-Dideoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.