Description

2',5'-Dideoxy-5'-[3,4-Dihydro-5-Methyl-2,4-Dioxopyrimidin-1(2H)-Yl]Uridine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for investigating novel antiviral and anticancer therapeutics. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the synthesis of nucleoside-based drugs, mechanism of action studies, and the development of targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex nucleoside analog drugs targeting viral and oncological diseases.
• Antiviral Research: Used as a precursor or reference standard in the development of novel antiviral agents, particularly against DNA viruses.
• Oncology Drug Discovery: Investigated for its potential incorporation into prodrugs or as a cytotoxic agent in cancer chemotherapy research.
• Biochemical Research: Employed in enzymatic studies to understand substrate specificity and inhibition mechanisms of nucleoside-processing enzymes.
• Reference Standard: Utilized as a high-purity analytical standard for quality control (QC) and method development in pharmaceutical analysis.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and reduce toxicity.

Basic Information

Item	Details
Product Name	2',5'-Dideoxy-5'-[3,4-Dihydro-5-Methyl-2,4-Dioxopyrimidin-1(2H)-Yl]Uridine
CAS No.	35959-40-1
Molecular Formula	C14H17N3O6
Molecular Weight	323.30 g/mol
Synonyms	5'-Deoxy-5'-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-2'-deoxyuridine; 2',5'-Dideoxy-5'-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)uridine; 5'-O-(3,4-Dihydro-5-methyl-2,4-dioxopyrimidin-1-yl)-2'-deoxyuridine; 2',5'-Dideoxyuridine derivative; 35959-40-1; Modified Nucleoside; DDU Derivative
EINECS	Contact for details

Quality Control

Our 2',5'-Dideoxy-5'-[3,4-Dihydro-5-Methyl-2,4-Dioxopyrimidin-1(2H)-Yl]Uridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.