Description

Pentafluorophenyl Isothiocyanate is a highly reactive and versatile fluorinated aromatic building block. This compound is critical for introducing the pentafluorophenyl isothiocyanate moiety into target molecules, enabling advanced material synthesis and biochemical labeling. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the stability and reactivity of the pentafluorophenyl group.
• Bioconjugation & Labeling: Serves as a derivatization agent for peptides, proteins, and other biomolecules in proteomics and diagnostic assay development.
• Polymer & Material Science: Building block for creating specialty polymers, liquid crystals, and advanced materials with unique thermal and chemical resistance properties.
• Analytical Chemistry: Employed as a derivatizing agent in chromatography (HPLC, GC) for the detection and quantification of amines and other nucleophiles.
• Cross-linking Agent: Facilitates the formation of stable covalent bonds in the synthesis of dendrimers, resins, and other cross-linked network structures.

Basic Information

Product Name	Pentafluorophenyl Isothiocyanate
CAS No.	35923-79-6
Molecular Formula	C7F5NS
Molecular Weight	249.14 g/mol
Synonyms	Perfluorophenyl Isothiocyanate; 2,3,4,5,6-Pentafluorophenyl Isothiocyanate; PFPITC; Pentafluorophenyl Mustard Oil; Isothiocyanic Acid, Pentafluorophenyl Ester; 1-Isothiocyanato-2,3,4,5,6-pentafluorobenzene
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl Isothiocyanate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.