Description

6α,7α-Epoxy-17-Hydroxycorticosterone 21-Acetate is a synthetic steroid derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial advanced intermediate in the synthesis of more complex corticosteroid molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel anti-inflammatory and immunosuppressive agents. The high-purity material is essential for ensuring the efficacy and safety of downstream pharmaceutical products.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Steroid Research: Used in academic and industrial laboratories to study structure-activity relationships (SAR) of glucocorticoid analogs.
• Process Chemistry: Employed in the development and scale-up of manufacturing routes for steroid-based therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical production.
• Biochemical Studies: Utilized in research investigating glucocorticoid receptor binding and metabolic pathways.

Basic Information

Product Name	6α,7α-Epoxy-17-Hydroxycorticosterone 21-Acetate
CAS No.	35875-74-2
Molecular Formula	C₂₃H₃₀O₇
Molecular Weight	418.48 g/mol
Synonyms	6α,7α-Epoxy-11β,17α,21-trihydroxypregn-4-ene-3,20-dione 21-acetate; 6α,7α-Epoxycortisol 21-acetate; 11β,17α,21-Trihydroxy-6α,7α-epoxypregn-4-ene-3,20-dione 21-acetate; (6α,7α,11β,17α)-6,7-Epoxy-11,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate; Cortisol 6α,7α-epoxide 21-acetate
EINECS	Contact for details

Quality Control

Our 6α,7α-Epoxy-17-Hydroxycorticosterone 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.