Description

9-α-Arabinofuranosyl-8-Azaadenine is a nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or reference standard for exploring novel antiviral and anticancer therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in nucleoside chemistry and the development of next-generation nucleic acid-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based antiviral or anticancer prodrugs.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies to investigate nucleoside metabolism and polymerase activity.
• Antiviral Agent Development: Investigated for its potential activity against viral pathogens by mimicking natural nucleosides and interfering with viral replication.
• Oncology Research: Explored in preclinical studies for its potential to inhibit cancer cell proliferation through incorporation into DNA/RNA or by targeting specific enzymes.
• Chemical Biology Tool: Utilized in the development of labeled probes or conjugates for diagnostic assays and target identification.
• Academic Research: Employed in universities and research institutes for fundamental studies in medicinal chemistry and nucleic acid science.

Basic Information

Product Name	9-α-Arabinofuranosyl-8-Azaadenine
CAS No.	35827-89-5
Molecular Formula	C9H10N6O4
Molecular Weight	266.22 g/mol
Synonyms	8-Azaadenine arabinoside; 9-α-D-Arabinofuranosyl-8-azaadenine; 8-Aza-9-(β-D-arabinofuranosyl)adenine; 8-Azaadenosine arabinoside; NSC 401005; 8-Aza-9-(α-D-arabinofuranosyl)adenine; 9-(α-D-Arabinofuranosyl)-8-azaadenine
EINECS	Contact for details

Quality Control

Our 9-α-Arabinofuranosyl-8-Azaadenine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide detailed Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.