Description

2-Hydroxy-2-Methylpropyl 4-(4-Amino-6,7,8-Trimethoxyquinazolin-2-Yl)Piperazine-1-Carboxylate Monohydrochloride is a high-purity, complex organic salt with significant pharmacological research interest. This compound matters as a key advanced intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of targeted drug candidates, particularly in oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Development: Functions as the active moiety in the formulation of preclinical and clinical trial materials.
• Biochemical Research: Employed in biochemical assays to study enzyme inhibition, receptor binding, and other molecular interactions.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to create more complex, specialized molecules for high-value applications.

Basic Information

Product Name	2-Hydroxy-2-Methylpropyl 4-(4-Amino-6,7,8-Trimethoxyquinazolin-2-Yl)Piperazine-1-Carboxylate Monohydrochloride
CAS No.	35795-17-6
Molecular Formula	C₂₂H₃₃ClN₆O₆
Molecular Weight	513.0 g/mol (approx.)
Synonyms	4-(4-Amino-6,7,8-trimethoxy-2-quinazolinyl)-1-piperazinecarboxylic acid 2-hydroxy-1,1-dimethylethyl ester monohydrochloride; 2-Hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate hydrochloride; 1-(2-Hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate hydrochloride; CAS 35795-17-6; Quinazoline derivative hydrochloride salt; 2-(4-Amino-6,7,8-trimethoxyquinazolin-2-yl)-1-piperazinecarboxylic acid 2-hydroxy-1,1-dimethylethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-Methylpropyl 4-(4-Amino-6,7,8-Trimethoxyquinazolin-2-Yl)Piperazine-1-Carboxylate Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.