Description

5'-N-Methylcarboxamidoadenosine is a stable adenosine derivative and a potent agonist of the adenosine A2A receptor. This compound is of significant value in biochemical and pharmacological research due to its ability to selectively modulate adenosine signaling pathways. It is primarily needed by researchers in the pharmaceutical, biotechnology, and academic sectors for applications in drug discovery, cardiovascular studies, and neurological research.

Application

• Pharmacological Research: Used as a reference standard and tool compound for studying adenosine A2A receptor-mediated effects.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis of novel therapeutics targeting cardiovascular and neurological disorders.
• Biochemical Assays: Employed in high-throughput screening (HTS) and in vitro assays to investigate receptor binding, activation, and downstream signaling cascades.
• Academic Research: Utilized in university and institutional labs for fundamental studies on purinergic signaling, inflammation, and immune response modulation.
• Reference Material: Acts as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	5'-N-Methylcarboxamidoadenosine
CAS No.	35788-27-3
Molecular Formula	C12H16N6O4
Molecular Weight	308.30 g/mol
Synonyms	MRS 4322; 5'-N-Methylcarboxamido adenosine; 2-[6-Amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-methylacetamide; N-Methyl-5'-carboxamidoadenosine; 5'-N-Methylcarbamoyladenosine; Adenosine, 5'-(N-methylcarboxamide)-; 5'-(N-Methylcarbamoyl)adenosine
EINECS	Contact for details

Quality Control

Our 5'-N-Methylcarboxamidoadenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.