Description

Tigloyl Chloride is a reactive acid chloride derivative of tiglic acid, serving as a crucial acylating agent and building block in advanced organic synthesis. Its high reactivity makes it indispensable for introducing the tigloyl moiety into target molecules, enabling the creation of compounds with specific stereochemistry and biological activity. This intermediate is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring the (E)-2-methyl-2-butenoyl functional group.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where specific acyl groups are needed for bioactivity.
• Fine Chemical Production: Serves as an acylating agent in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials.
• Research & Development: Essential reagent in organic chemistry labs for method development and the creation of novel chemical entities in medicinal chemistry.
• Polymer Modification: Employed to modify polymers and resins by introducing functional side chains to alter physical or chemical properties.

Basic Information

Item	Detail
Product Name	Tigloyl Chloride
CAS No.	35660-94-7
Molecular Formula	C5H7ClO
Molecular Weight	118.56 g/mol
Synonyms	(E)-2-Methyl-2-butenoyl chloride; Tiglic acid chloride; trans-2-Methyl-2-butenoyl chloride; 2-Methylcrotonoyl chloride; (E)-2-Methylbut-2-enoyl chloride
EINECS	Contact for details

Quality Control

Our Tigloyl Chloride is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical B2B supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.