Description

5-Methoxyuridine is a modified nucleoside derivative where a methoxy group is substituted at the 5-position of the uracil base. This structural modification is crucial for its role as a key intermediate and building block in the synthesis of more complex nucleoside analogs and oligonucleotides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic probes, and biochemical research tools.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of antiviral and anticancer nucleoside drugs.
• Biochemical Research: Used as a modified nucleotide in studies of RNA structure, function, and metabolism.
• Oligonucleotide Synthesis: Acts as a specialized building block for introducing specific modifications into synthetic DNA or RNA strands.
• Probe Development: Employed in the creation of labeled nucleotides for diagnostic assays and genomic research.
• Enzyme Substrate Studies: Utilized to investigate the activity and specificity of nucleoside-metabolizing enzymes.
• Reference Standard: Functions as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-Methoxyuridine
CAS No.	35542-01-9
Molecular Formula	C10H14N2O7
Molecular Weight	274.23 g/mol
Synonyms	5-Methoxy-1-β-D-ribofuranosyluracil; 1-(β-D-Ribofuranosyl)-5-methoxyuracil; 5-Methoxy-Uridine; 5-Methoxyuridine, 1-β-D-Ribofuranosyl-5-methoxyuracil; Uridine, 5-methoxy-
EINECS	Contact for details

Quality Control

Our 5-Methoxyuridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.