Description

3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-14-Hydroxycarda-5,20(22)-Dienolide is a specialized cardiac glycoside derivative, a class of compounds known for their potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the study of cardiovascular therapeutics and novel drug discovery. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis of advanced active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycoside-based drugs and their analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac function.
• API Development: Serves as a critical precursor in the research and development of new Active Pharmaceutical Ingredients (APIs) targeting heart failure and arrhythmias.
• Pharmacological Studies: Employed in in vitro and in vivo models to explore structure-activity relationships (SAR) within the cardenolide class.
• Reference Standard: Provides a high-purity compound for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-14-Hydroxycarda-5,20(22)-Dienolide
CAS No.	35536-76-6
Molecular Formula	C₂₉H₄₂O₉
Molecular Weight	534.64 g/mol
Synonyms	14-Hydroxy-3β-[(6-deoxy-α-L-mannopyranosyl)oxy]carda-5,20(22)-dienolide; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Desglucouzarin; Uzarigenin 3-O-α-L-rhamnoside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14-hydroxy-5,20(22)-cardenolide; 14-Hydroxyuzarigenin α-L-rhamnoside; Uzarigenin α-L-rhamnoside; 3-O-α-L-Rhamnopyranosyl-14-hydroxy-5,20(22)-cardenolide
EINECS	Contact for details

Quality Control

Our 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-14-Hydroxycarda-5,20(22)-Dienolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.