Description

12α-Acetoxy-5α-Androstane is a high-purity steroid derivative and a key synthetic intermediate in organic chemistry. This compound is valued for its defined stereochemistry and functional group, which are critical for the precise synthesis of more complex steroid-based molecules. It is primarily required by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic agents, reference standards, and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and other steroid-based drugs.
• Research & Development: Used in academic and industrial laboratories for medicinal chemistry research, exploring new biological pathways and therapeutic targets.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Tool Compound: Utilized in life science research to study steroid hormone receptors, enzyme inhibition, and metabolic pathways.
• Fine Chemical Synthesis: An intermediate for producing other specialized androstane derivatives with modified biological activity.

Basic Information

Product Name	12α-Acetoxy-5α-Androstane
CAS No.	35487-69-5
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	5α-Androstan-12α-ol, acetate; 12α-Acetoxyandrostane; Androstane-12α-ol acetate; 12α-Acetoxy-5α-androstane; 5α,12α-Androstanediol 12-acetate
EINECS	Contact for details

Quality Control

Our 12α-Acetoxy-5α-Androstane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.