Description

Cholesterol 7 β-Hydroperoxide is a specific oxidized derivative of cholesterol, a key intermediate in the study of lipid peroxidation and oxidative stress pathways. This compound is of significant value for researchers and manufacturers investigating the mechanisms of cholesterol oxidation, its biological effects, and its role in various disease models. It serves as a critical reference standard and starting material for pharmaceutical R&D, analytical laboratories, and biochemical studies focused on cardiovascular health, aging, and metabolic disorders.

Application

• Biochemical Research: Used as a key intermediate and reference standard in studies of cholesterol oxidation pathways and lipid peroxidation mechanisms.
• Pharmaceutical Development: Serves as a starting material or analytical standard in the research of drugs targeting oxidative stress-related conditions, such as atherosclerosis and neurodegenerative diseases.
• Analytical Chemistry: Employed as a high-purity standard for calibrating instruments (HPLC, GC-MS) and developing methods to quantify cholesterol oxidation products (COPs) in food, biological, and pharmaceutical samples.
• Nutraceutical & Food Safety: Acts as a marker compound for assessing the extent of cholesterol oxidation in food products (e.g., dairy, eggs, meats) to ensure quality and safety.
• Cosmetic Science: Utilized in research to understand the oxidative degradation of cholesterol-based ingredients and their stability in formulations.
• Diagnostic Reagent Manufacturing: A potential component in the development of diagnostic kits and assays designed to measure oxidative stress biomarkers.

Basic Information

Product Name	Cholesterol 7 β-Hydroperoxide
CAS No.	35455-44-8
Molecular Formula	C₂₇H₄₆O₃
Molecular Weight	418.66 g/mol
Synonyms	7β-Hydroperoxycholest-5-en-3β-ol; 7β-Hydroperoxycholesterol; Cholest-5-ene-3β,7β-diol 7-hydroperoxide; 3β-Hydroxycholest-5-en-7β-hydroperoxide; Cholesterol 7β-OOH; 7β-OOH Cholesterol; 7β-HPCh; A major cholesterol hydroperoxide
EINECS	Contact for details

Quality Control

Our Cholesterol 7 β-Hydroperoxide is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and analytical applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize degradation due to its easily oxidized nature. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in chloroform, DMSO; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.