Description

1-Naphthalenecarbonyl Fluoride (9Ci) is a specialized fluorinated aromatic building block used in advanced organic synthesis. This compound is valued for its reactivity as an acyl fluoride, enabling efficient coupling reactions to construct complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with naphthalene-based scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides requiring specific fluorinated motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Cross-Coupling Reactions: Acts as an efficient acylating agent in Suzuki, Stille, and other metal-catalyzed cross-coupling reactions.
• Fluorination Chemistry: Employed as a source of the carbonyl fluoride group for introducing fluorinated functionalities into target molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	1-Naphthalenecarbonyl Fluoride (9Ci)
CAS No.	35424-74-9
Molecular Formula	C11H7FO
Molecular Weight	174.17 g/mol
Synonyms	1-Naphthoyl Fluoride; Naphthalene-1-carbonyl Fluoride; α-Naphthoyl Fluoride; 1-Fluorocarbonylnaphthalene; 1-Carboxyfluoronaphthalene; 1-Naphthalenecarboxylic Acid Fluoride; 1-Naphthoic Acid Fluoride
EINECS	Contact for details

Quality Control

Our 1-Naphthalenecarbonyl Fluoride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.