Description

3-Nitrocinnamoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the nitro and acyl chloride functional groups, enabling efficient formation of amides and esters for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators by introducing the nitrocinnamoyl moiety.
• Peptide Mimetics & Conjugation: Facilitates the acylation of amino groups in amino acids or peptides to create modified peptide chains or protein conjugates for biochemical research.
• Liquid Crystal & OLED Material Research: Acts as a building block for synthesizing advanced organic molecules with specific optical and electronic properties for display technologies.
• Polymer Chemistry: Employed in the production of specialty polymers and coatings, where it can be incorporated as a monomer to impart specific chemical resistance or stability.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing complex azo dyes and organic pigments with enhanced color fastness and performance.

Basic Information

Product Name	3-Nitrocinnamoyl Chloride
CAS No.	35418-05-4
Molecular Formula	C9H6ClNO3
Molecular Weight	211.60 g/mol
Synonyms	(E)-3-(3-Nitrophenyl)acryloyl chloride; trans-3-Nitrocinnamoyl chloride; 3-Nitro-trans-cinnamoyl chloride; (2E)-3-(3-Nitrophenyl)prop-2-enoyl chloride; 3-Nitrocinnamic acid chloride; β-(3-Nitrophenyl)acryloyl chloride; Cinnamoyl chloride, 3-nitro-
EINECS	Contact for details

Quality Control

Our 3-Nitrocinnamoyl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.