Description

3,4,5-Trihydroxybenzoyl Chloride is a key acyl chloride derivative of gallic acid, serving as a versatile and reactive synthetic intermediate. Its primary value lies in enabling the efficient introduction of the 3,4,5-trihydroxybenzoyl moiety into target molecules, which is crucial for modifying physicochemical properties and biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs), antioxidants, and advanced polymer precursors.

Application

• Pharmaceutical Synthesis: A critical building block for the production of active pharmaceutical ingredients (APIs), including gallate ester prodrugs and molecules targeting metabolic pathways.
• Agrochemical Intermediates: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that leverage the antioxidant properties of the galloyl group.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, resins, and coatings with enhanced thermal stability or UV resistance.
• Antioxidant & Cosmetic Ingredients: A precursor for synthesizing high-purity antioxidants, stabilizers, and active ingredients for cosmetic and personal care formulations.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling proteins, peptides, and other biomolecules due to its reactive acid chloride group.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments, particularly those requiring specific hydroxyl substitution patterns.

Basic Information

Product Name	3,4,5-Trihydroxybenzoyl Chloride
CAS No.	35388-10-4
Molecular Formula	C7H5ClO4
Molecular Weight	188.56 g/mol
Synonyms	Gallic Acid Chloride; 3,4,5-Trihydroxybenzoyl Chloride; Galloyl Chloride; 3,4,5-Trihydroxybenzoic Acid Chloride; Benzoyl chloride, 3,4,5-trihydroxy-; 3,4,5-Trihydroxybenzoic chloride
EINECS	Contact for details

Quality Control

Our 3,4,5-Trihydroxybenzoyl Chloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee supply reliability and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.