Description

4-Chloro-2,3,5,6-Tetrafluorobenzylalcohol is a highly functionalized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of a reactive benzyl alcohol group with a perhalogenated, electron-deficient benzene ring, enabling precise molecular modifications. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Used in the development of fluorinated components for advanced display technologies due to its polarizability and stability.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, nucleophilic substitutions, and oxidation reactions to introduce fluorinated aromatic segments.
• Material Science Research: Investigated for use in organic semiconductors and as a ligand precursor in catalysis.

Basic Information

Product Name	4-Chloro-2,3,5,6-Tetrafluorobenzylalcohol
CAS No.	35175-80-5
Molecular Formula	C7H3ClF4O
Molecular Weight	214.55 g/mol
Synonyms	(4-Chloro-2,3,5,6-tetrafluorophenyl)methanol; 2,3,5,6-Tetrafluoro-4-chlorobenzyl Alcohol; α,2,3,5,6-Pentafluoro-4-chlorotoluene; 4-Chlorotetrafluorobenzyl Alcohol; 4-Chloro-2,3,5,6-tetrafluorobenzyl Alcohol; Pentafluorochlorobenzyl Alcohol (ambiguous); 4-Chloro-α,2,3,5,6-pentafluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3,5,6-Tetrafluorobenzylalcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be hygroscopic; handle under inert atmosphere for critical applications.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.