Description

2-Iodoadenosine is a halogenated nucleoside derivative of adenosine, where a hydrogen atom is substituted with an iodine atom at the 2-position of the purine ring. This modification is critical for its role as a versatile building block and intermediate in synthetic organic chemistry and medicinal research. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of adenosine receptor ligands and other nucleoside-based drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate adenosine-related metabolic pathways.
• Radiopharmaceuticals: Serves as a starting material for the development of iodine-123 or iodine-131 labeled compounds for diagnostic imaging or therapy.
• Antiviral & Anticancer Agent Development: Explored in research for creating modified nucleosides with potential biological activity.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) due to the reactive carbon-iodine bond.
• Labeling & Tracing Studies: Employed to introduce an iodine tag into larger molecules for tracking and analytical purposes.

Basic Information

Product Name	2-Iodoadenosine
CAS No.	35109-88-7
Molecular Formula	C10H11IN5O4
Molecular Weight	392.13 g/mol
Synonyms	2-Iodo-9-β-D-ribofuranosyl-9H-purin-6-amine; 2-Iodo-9-β-D-ribofuranosyladenine; 2-Iodoadenine riboside; Adenosine, 2-iodo-; 2-I-Ado; 2-Iodo-9-(β-D-ribofuranosyl)adenine; 2-I-adenosine
EINECS	Contact for details

Quality Control

Our 2-Iodoadenosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.