Description

2-Amino-6-Chloro-9-(3,5-Di-o-(p-Toluoyl)-β-D-2-Deoxyribofurnanosyl)Purine is a sophisticated nucleoside analog intermediate of significant importance in advanced pharmaceutical research and development. Its core value lies in its role as a key building block for the synthesis of modified nucleosides and nucleotides, which are crucial for developing novel antiviral and anticancer therapeutics. This high-purity intermediate is essential for research institutions and pharmaceutical companies engaged in the creation of next-generation active pharmaceutical ingredients (APIs). The compound, CAS NO 35095-93-3, enables precise molecular modifications critical for optimizing drug efficacy and pharmacokinetic profiles.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel purine-based antiviral and anticancer agents.
• Antiviral Drug Research: Used in the development of nucleoside analogs targeting viral polymerases for diseases such as hepatitis and herpes.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA replication in cancer cells.
• Biochemical Probe Synthesis: Utilized to create labeled or modified nucleosides for studying enzyme mechanisms and cellular processes.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale production of experimental drug candidates before commercial manufacturing.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes exploring new pathways in medicinal chemistry and nucleotide chemistry.

Basic Information

Item	Details
Product Name	2-Amino-6-Chloro-9-(3,5-Di-o-(p-Toluoyl)-β-D-2-Deoxyribofurnanosyl)Purine
CAS No.	35095-93-3
Molecular Formula	C31H28ClN5O5
Molecular Weight	586.04 g/mol
Synonyms	2-Amino-6-chloro-9-[(2R,3S,5R)-3,5-bis(4-methylbenzoyloxy)-2-(hydroxymethyl)tetrahydrofuran-2-yl]-9H-purine; 2-Amino-6-chloro-9-[3,5-di-O-(p-toluoyl)-β-D-2-deoxyribofuranosyl]purine; 2-Amino-6-chloropurine 2'-deoxyriboside 3',5'-di-p-toluate; 6-Chloro-2-aminopurine 2-deoxyriboside 3',5'-di-p-toluoyl ester; 2'-Deoxy-2-amino-6-chloropurine riboside 3',5'-ditoluenoate; 9-[(2R,3S,5R)-3,5-Bis(4-methylbenzoyloxy)tetrahydrofuran-2-yl]-6-chloro-9H-purin-2-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloro-9-(3,5-Di-o-(p-Toluoyl)-β-D-2-Deoxyribofurnanosyl)Purine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.