Description

N-(4-Isothiocyanato-Phenyl)-Acetamide is a specialized organic compound featuring a reactive isothiocyanate group, making it a valuable intermediate for chemical synthesis. This compound is critical for researchers and manufacturers requiring a precise building block to introduce the phenylacetamide-isothiocyanate moiety into larger molecular frameworks. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where specific functionalization is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Probe Development: The reactive isothiocyanate group enables covalent bonding to amines, useful for creating fluorescent probes, affinity labels, and antibody-drug conjugates (ADCs).
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Chemical Research: A versatile reagent in organic synthesis for constructing heterocycles and complex organic molecules.

Basic Information

Product Name	N-(4-Isothiocyanato-Phenyl)-Acetamide
CAS No.	35008-62-9
Molecular Formula	C9H8N2OS
Molecular Weight	192.24 g/mol
Synonyms	4-Acetamidophenyl Isothiocyanate; p-Acetamidophenyl Isothiocyanate; 1-(4-Isothiocyanatophenyl)ethan-1-one; N-(4-Isothiocyanatophenyl)acetamide; Acetamide, N-[4-(isothiocyanato)phenyl]-; 4-Isothiocyanatoacetanilide; NSC 403014
EINECS	Contact for details

Quality Control

Our N-(4-Isothiocyanato-Phenyl)-Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.