Description

2-Amino-9-α-D-Arabinofuranosyl-1,9-Dihydro-6H-Purin-6-One CAS NO 34793-16-3 is a high-purity nucleoside analog, a key intermediate in the synthesis of antiviral and anticancer pharmaceuticals. Its precise chemical structure is critical for research and development in targeted therapeutic applications. This compound is essential for pharmaceutical manufacturers, biotechnology research institutions, and academic laboratories focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of antiviral and anticancer active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies and metabolic pathway research.
• Nucleoside Chemistry: Serves as a precursor for the development of novel modified nucleosides with potential therapeutic activity.
• Antiviral Drug Development: Integral to R&D programs targeting viruses, leveraging its arabinofuranosyl structure.
• Oncology Research: Investigated for its role in creating compounds that interfere with DNA/RNA synthesis in cancer cells.
• Process Development: Employed in scaling up synthetic routes for GMP production of final drug substances.

Basic Information

Product Name	2-Amino-9-α-D-Arabinofuranosyl-1,9-Dihydro-6H-Purin-6-One
CAS No.	34793-16-3
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	9-β-D-Arabinofuranosylguanine; Ara-G; Vidarabine Impurity; Vidarabine Related Compound A; 2-Amino-9-β-D-arabinofuranosyl-9H-purin-6-ol; 2-Amino-9-β-D-arabinofuranosylhypoxanthine; β-D-Arabinofuranosylguanine; Guanine Arabinoside
EINECS	Contact for details

Quality Control

Our 2-Amino-9-α-D-Arabinofuranosyl-1,9-Dihydro-6H-Purin-6-One is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.