Description

2-Phenoxyethyl Chloroformate is a versatile and highly reactive chloroformate ester, a key reagent in organic synthesis. Its primary value lies in its role as a protecting group and activating agent for carboxylic acids and amines, facilitating the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to build active pharmaceutical ingredients (APIs), advanced intermediates, and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for the preparation of carbamate and carbonate derivatives, which are common motifs in drug molecules.
• Peptide Chemistry: Used as a coupling agent or for introducing the phenoxyethyloxycarbonyl (Poc) protecting group for amino acids.
• Agrochemical Production: Employed in the synthesis of herbicides, fungicides, and insecticides that require carbamate or specific ester functionalities.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry and process development for novel compounds.
• Dye and Pigment Manufacturing: Utilized in the synthesis of advanced colorants and photoactive materials.

Basic Information

Product Name	2-Phenoxyethyl Chloroformate
CAS No.	34743-87-8
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	Ethylene Glycol Phenylether Chloroformate; 2-Phenoxyethyl Carbonochloridate; Phenoxyethyl Chloroformate; 2-Phenoxyethoxycarbonyl Chloride; (2-Phenoxyethoxy)carbonyl Chloride; Chloroformic Acid 2-Phenoxyethyl Ester; Poc-Cl; 34743-87-8
EINECS	Contact for details

Quality Control

Every batch of our 2-Phenoxyethyl Chloroformate is produced and tested under strict quality management protocols. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.