Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2S,4R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. Its rigid norbornene framework and reactive acid chloride functionality make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced chiral pesticides and herbicides, where its specific stereochemistry can influence biological activity and environmental profile.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Employed as a monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties, such as those used in advanced coatings or composites.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, enabling studies in cycloaddition reactions and stereoselective transformations.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and flavors & fragrances requiring high stereochemical purity.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride, (1R,2S,4R)-Rel- (9Ci)
CAS No.	34733-86-3
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	(1R,2S,4R)-Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; (-)-exo-5-Norbornene-2-carbonyl chloride; (1R,2S,4R)-(-)-5-Norbornene-2-carbonyl chloride; exo-(-)-Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride; (1R,2S,4R)-rel-5-Norbornen-2-carbonylchlorid; Chiral Norbornene Acid Chloride; endo-5-Norbornene-2-carbonyl chloride isomer (related); Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, (1R,2S,4R)-(-)-
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Chloride is manufactured and tested under strict quality management systems to ensure high chiral purity and chemical consistency. Our standard quality control protocol includes comprehensive analysis by HPLC, GC, and NMR spectroscopy to verify identity, assay, enantiomeric excess (ee), and impurity profiles. Certificates of Analysis (COA) detailing all test results are provided with each shipment, and we support custom purity specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids, bases, and oxidizing agents. Handle and store only in compatible, dry organic solvent-resistant containers.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.