Description

Urapidil 5-Methyl- CAS NO 34661-85-3 is a high-purity pharmaceutical intermediate and research chemical, specifically the 5-methyl derivative of the antihypertensive agent urapidil. This compound is of significant value for the development and synthesis of novel active pharmaceutical ingredients (APIs) and for advanced pharmacological research. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in cardiovascular drug discovery and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of urapidil analogs and related antihypertensive agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new α-1 adrenergic receptor antagonists.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Biochemical Research: Employed in pharmacological assays to study receptor binding and cardiovascular mechanisms.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex organic molecules for preclinical development.

Basic Information

Product Name	Urapidil 5-Methyl- CAS NO 34661-85-3
CAS No.	34661-85-3
Molecular Formula	C20H29N5O3
Molecular Weight	387.48 g/mol
Synonyms	5-Methylurapidil; 6-({3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3-dimethyl-5-methylpyrimidine-2,4(1H,3H)-dione; 1,3-Dimethyl-6-({3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl}amino)-5-methyl-2,4(1H,3H)-pyrimidinedione; Urapidil Impurity; Urapidil Related Compound; CRM for Urapidil; 5-Methyl Urapidil
EINECS	Contact for details

Quality Control

Our Urapidil 5-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade standards suitable for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.