Description

3-Chloro-6-Fluorobenzothiophene-2-Carbonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the benzothiophene core, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Used in the creation of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Serves as a scaffold for developing fluorescent tags and molecular probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and specialty chemicals.

Basic Information

Product Name	3-Chloro-6-Fluorobenzothiophene-2-Carbonyl Chloride
CAS No.	34576-83-5
Molecular Formula	C9H3Cl2FOS
Molecular Weight	249.09 g/mol
Synonyms	2-Chlorocarbonyl-3-chloro-6-fluorobenzothiophene; 3-Chloro-6-fluoro-2-benzothiophenecarbonyl chloride; 3-Chloro-6-fluorobenzo[b]thiophene-2-carbonyl chloride; 34576-83-5; 3-Chloro-6-fluoro-1-benzothiophene-2-carbonyl chloride; 6-Fluoro-3-chlorobenzothiophene-2-carbonyl chloride; 3-Chloro-6-fluorothianaphthene-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-6-Fluorobenzothiophene-2-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.