Description

3-Chloro-6-Nitro-1-Benzothiophene-2-Carbonyl Chloride is a high-purity, reactive chemical intermediate characterized by its dual functional groups, making it a versatile building block for complex synthesis. This compound is critical for the development of advanced materials and active pharmaceutical ingredients (APIs) where precise molecular architecture is required. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the benzothiophene core for biological activity.
• Material Science Research: Serves as a building block for organic semiconductors, dyes, and photoactive materials due to its electron-accepting nitro and carbonyl chloride groups.
• Chemical Biology Probes: Employed in the creation of tagged molecules and activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing specialized compounds for client R&D projects.

Basic Information

Product Name	3-Chloro-6-Nitro-1-Benzothiophene-2-Carbonyl Chloride
CAS No.	34576-82-4
Molecular Formula	C9H3Cl2NO3S
Molecular Weight	276.09 g/mol
Synonyms	3-Chloro-6-nitrobenzo[b]thiophene-2-carbonyl chloride; 2-Benzothiophenecarbonyl chloride, 3-chloro-6-nitro-; 3-Chloro-6-nitro-1-benzothiophene-2-carboxylic acid chloride; 3-Chloro-6-nitrothianaphthene-2-carbonyl chloride; 34576-82-4; 3-Chloro-6-nitrobenzo[b]thiophene-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Nitro-1-Benzothiophene-2-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.