Description

8-Chloroadenosine is a halogenated nucleoside analog of significant interest in medicinal chemistry and biochemical research. This compound serves as a versatile building block and a key intermediate in the synthesis of more complex adenosine receptor ligands and other pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for targeting purinergic signaling pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel adenosine receptor agonists and antagonists for therapeutic development.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate kinase and phosphorylase activity.
• Nucleoside Chemistry: Serves as a key starting material for the preparation of other modified nucleosides and nucleotides.
• Antiviral/Anticancer Agent Development: Explored for its potential as a lead compound in the design of antiviral and antiproliferative drugs.
• Labeled Compound Synthesis: Used in the preparation of radiolabeled or fluorescently tagged analogs for tracer and diagnostic studies.
• Academic & Industrial R&D: Fundamental research tool in universities and corporate labs studying cell signaling, metabolism, and nucleotide analogs.

Basic Information

Product Name	8-Chloroadenosine
CAS No.	34408-14-5
Molecular Formula	C10H12ClN5O4
Molecular Weight	301.69 g/mol
Synonyms	8-Chloro-9-β-D-ribofuranosyl-9H-purin-6-amine; 8-Chloroadenine riboside; 8-Cl-Ado; Adenosine, 8-chloro-; 8-Chloro-9-β-D-ribofuranosyladenine; 6-Amino-8-chloro-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our 8-Chloroadenosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.