Description

(R)-(-)-Mepivacaine Monohydrochloride is the pure enantiomeric salt form of the local anesthetic agent mepivacaine. This high-purity chiral intermediate is critical for research and development in stereoselective pharmacology and advanced drug formulation. It is primarily utilized by pharmaceutical R&D laboratories, analytical reference standard producers, and manufacturers developing enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of enantiomerically pure local anesthetic formulations.
• Analytical Reference Standard: Used in HPLC, GC, and chiral chromatography for method development, validation, and quality control testing of mepivacaine-based products.
• Pharmacology Research: Essential for studying the stereospecific activity, metabolism, and receptor binding profiles of the (R)-enantiomer of mepivacaine.
• Process Development: Employed in the development and scaling of asymmetric synthesis and purification processes within API manufacturing.
• Regulatory Submissions: Provides a characterized impurity standard or starting material for drug master files (DMFs) and regulatory documentation.

Basic Information

Product Name	(R)-(-)-Mepivacaine Monohydrochloride
CAS No.	34333-72-7
Molecular Formula	C15H23N2O•HCl
Molecular Weight	282.82 g/mol (Free base: 246.36)
Synonyms	(R)-(-)-1-Methyl-2',6'-pipecoloxylidide Monohydrochloride; (R)-Mepivacaine HCl; (-)-Mepivacaine Hydrochloride; (R)-2,6-Dimethyl-N-(2,6-dimethylphenyl)piperidine-1-carboxamide Hydrochloride; Carbocaine (R)-Enantiomer Hydrochloride; Scandonest (R)-Enantiomer Hydrochloride; Polocaine (R)-Enantiomer Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(-)-Mepivacaine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling by HPLC, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (Anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.