Description

Dibenz[B,F]Azepine-5-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the creation of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tricyclic compounds and other complex heterocycles with potential biological activity.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its fused ring structure.
• Material Science: Serves as a monomer or building block for specialty polymers and advanced organic materials.
• Academic & Industrial R&D: Employed in method development and exploratory chemistry for creating new chemical entities.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	Dibenz[B,F]Azepine-5-Carbonyl Chloride
CAS No.	33948-22-0
Molecular Formula	C15H10ClNO
Molecular Weight	255.70 g/mol
Synonyms	5-Carboxyldibenz[b,f]azepine Chloride; Dibenz[b,f]azepine-5-carbonyl chloride; 5H-Dibenz[b,f]azepine-5-carbonyl chloride; 10,11-Dihydro-5H-dibenzo[b,f]azepine-5-carbonyl chloride; Imipramine Acid Chloride; Imipramine Carbonyl Chloride; 5-Chlorocarbonyl-5H-dibenzo[b,f]azepine
EINECS	Contact for details

Quality Control

Our Dibenz[B,F]Azepine-5-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.