Description

(22R)-5,17,22-Trihydroxy-1-Oxo-5α-Ergosta-2,6,24-Trien-26-Oic Acid δ-Lactone is a highly functionalized ergostane-type steroidal lactone, valued for its complex molecular architecture and biological relevance. This compound serves as a critical advanced intermediate or reference standard in pharmaceutical research and development, particularly for studying sterol biosynthesis and metabolic pathways. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents or bioactive natural product derivatives.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and bioactive molecules targeting metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studies of sterol and steroid hormone biosynthesis pathways.
• Natural Product Chemistry: Serves as a model compound or precursor for the semi-synthesis of complex natural products with ergostane skeletons.
• Analytical Standard: Employed in method development and quality control (HPLC, LC-MS) for the identification and quantification of related steroidal compounds.
• Enzyme Inhibition Studies: Investigated for potential activity against enzymes involved in sterol metabolism, such as cytochrome P450 enzymes.

Basic Information

Product Name	(22R)-5,17,22-Trihydroxy-1-Oxo-5α-Ergosta-2,6,24-Trien-26-Oic Acid δ-Lactone
CAS No.	33903-20-7
Molecular Formula	C28H38O6
Molecular Weight	470.60 g/mol
Synonyms	5,17,22-Trihydroxy-1-oxoergosta-2,6,24-trien-26-oic acid δ-lactone; (22R)-Ergosta-2,6,24-trien-26-oic acid, 5,17,22-trihydroxy-1-oxo-, δ-lactone; 5α-Ergosta-2,6,24-trien-26-oic acid, 5,17,22-trihydroxy-1-oxo-, δ-lactone, (22R)-; A derivative of Ergosta-2,6,24-trien-26-oic acid δ-lactone.
EINECS	Contact for details

Quality Control

Our (22R)-5,17,22-Trihydroxy-1-Oxo-5α-Ergosta-2,6,24-Trien-26-Oic Acid δ-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full transparency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.