Description

(1R)-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ-Dimethyl-7β-(1-Methylethyl)-1-Phenanthrenecarboxylic Acid Methyl Ester is a high-purity, complex diterpenoid ester with a defined stereochemistry, serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a structurally sophisticated scaffold for the research and development of novel bioactive compounds, particularly within the pharmaceutical sector. This product is essential for R&D chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries seeking to build upon its intricate fused-ring system.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting steroid-like receptors or requiring complex polycyclic frameworks.
• Agrochemical Research: Used in the development of new plant growth regulators or pesticides that leverage diterpenoid chemistry for enhanced biological activity.
• Fine Chemical Synthesis: Serves as a chiral starting material or intermediate for producing specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional R&D: A valuable reference standard and synthetic tool for studies in natural product chemistry, total synthesis, and medicinal chemistry.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for complex organic molecules in a GMP or non-GMP environment.

Basic Information

Item	Detail
Product Name	(1R)-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ-Dimethyl-7β-(1-Methylethyl)-1-Phenanthrenecarboxylic Acid Methyl Ester
CAS No.	33892-15-8
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Methyl (1R,4aS,7R,10aR)-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydrophenanthrene-1-carboxylate; 7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydrophenanthrene-1-carboxylic acid methyl ester; (1R,4aS,7R,10aR)-1,4a-Dimethyl-7-isopropyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydrophenanthrene-1-carboxylic acid methyl ester; Abietic acid methyl ester derivative; Diterpene ester intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of (1R)-1,2,3,4,4A,5,6,7,8,9,10,10Aα-Dodecahydro-1,4Aβ-Dimethyl-7β-(1-Methylethyl)-1-Phenanthrenecarboxylic Acid Methyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and purity for research and development applications. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. While typically supplied as a high-purity research-grade material, specifications can be aligned with GMP or ICH guidelines for advanced pharmaceutical development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Optical Rotation	Specific range available on COA
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.