Description

2,2'-Anhydro-1-(β-D-Arabinofuranosyl)Orotic Acid Ethyl Ester is a key nucleoside intermediate with significant synthetic utility. This compound is valued for its role as a versatile building block in the preparation of modified nucleosides and related pharmaceutical actives. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analogs and prodrugs for therapeutic development.
• Antiviral Research: Used in the research and development of potential antiviral agents targeting viral polymerases.
• Anticancer Agent Synthesis: Serves as a building block for creating nucleoside-based compounds investigated for their antitumor properties.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolism and related pathways.
• Process Chemistry: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) in GMP environments.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	2,2'-Anhydro-1-(β-D-Arabinofuranosyl)Orotic Acid Ethyl Ester
CAS No.	33780-80-2
Molecular Formula	C12H14N2O7
Molecular Weight	298.25 g/mol
Synonyms	2,2'-Anhydro-1-β-D-arabinofuranosylorotic Acid Ethyl Ester; 1-(2,2-Anhydro-β-D-arabinofuranosyl)orotic Acid Ethyl Ester; Ethyl 2,2'-Anhydro-1-β-D-arabinofuranosylorotate; Ara-Cytidine Orotate Ethyl Ester Derivative; Anhydroarabinofuranosyl Orotate Ethyl Ester; NSC 154020; Orotic acid, 1-(2,2-anhydro-β-D-arabinofuranosyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 2,2'-Anhydro-1-(β-D-Arabinofuranosyl)Orotic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.