Description

(13α,17α,20S,23R,24R)-21,24-Epoxy-4,4,8-Trimethyl-5α-Cholest-14-Ene-3α,7α,23,25-Tetrol is a high-purity, complex steroidal epoxide compound of significant interest in advanced chemical synthesis and pharmaceutical research. Its unique polycyclic structure with multiple hydroxyl groups and an epoxy bridge makes it a valuable key intermediate for developing novel bioactive molecules. This compound is primarily sought by research institutions and pharmaceutical R&D departments for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroidal drugs and therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Employed in studies investigating sterol biosynthesis pathways, enzyme inhibition, and receptor binding assays.
• Reference Standard: Utilized as an analytical standard for quality control and method development in laboratories analyzing complex steroidal mixtures.
• Process Chemistry Development: Acts as a key intermediate for scaling up synthetic routes to more complex natural product derivatives.
• Academic Research: Used in universities and research institutes for synthetic organic chemistry projects and the exploration of new chemical transformations.

Basic Information

Product Name	(13α,17α,20S,23R,24R)-21,24-Epoxy-4,4,8-Trimethyl-5α-Cholest-14-Ene-3α,7α,23,25-Tetrol
CAS No.	33573-46-5
Molecular Formula	C₃₀H₅₀O₅
Molecular Weight	490.72 g/mol
Synonyms	21,24-Epoxy-4,4,8-trimethylcholest-14-ene-3,7,23,25-tetrol; (13α,17α,20S,23R,24R)-21,24-Epoxy-4,4,8-trimethylcholest-14-ene-3α,7α,23,25-tetrol; 3α,7α,23,25-Tetrahydroxy-21,24-epoxy-4,4,8-trimethyl-5α-cholest-14-ene; A derivative of Withanolide / Physalin; Steroidal Epoxide Tetrol.
EINECS	Contact for details

Quality Control

Our (13α,17α,20S,23R,24R)-21,24-Epoxy-4,4,8-Trimethyl-5α-Cholest-14-Ene-3α,7α,23,25-Tetrol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.