Description

Thymidine-5'-Monophosphate Disodium Salt is a high-purity nucleotide building block essential for life science research and pharmaceutical development. This compound serves as a critical precursor in the synthesis of oligonucleotides, DNA probes, and various biochemical reagents. It is primarily utilized by researchers and manufacturers in the biotechnology, pharmaceutical, and molecular diagnostics industries.

Application

• Oligonucleotide Synthesis: A key monomer (dTMP) for solid-phase synthesis of DNA and primers.
• Biochemical Research: Substrate for enzymatic studies involving kinases, phosphatases, and polymerases.
• Diagnostic Reagent Manufacturing: Used in the production of labeled probes for PCR, sequencing, and microarray applications.
• Cell Culture Media: Component of specialized media formulations for nucleotide-deficient cell lines.
• Pharmaceutical Intermediates: Starting material for the synthesis of antiviral and anticancer nucleoside analogs.
• Reference Standard: Serves as an analytical standard in quality control laboratories for HPLC and mass spectrometry.

Basic Information

Product Name	Thymidine-5'-Monophosphate Disodium Salt
CAS No.	33430-62-5
Molecular Formula	C10H13N2Na2O8P
Molecular Weight	368.16 g/mol
Synonyms	5'-TMP Disodium Salt; dTMP-Na2; Thymidylic Acid Disodium Salt; Thymidine 5'-(Disodium Phosphate); 2'-Deoxythymidine-5'-monophosphate Disodium Salt; dThd-5'-P Disodium; TMP-Na2; 5'-Thymidylic Acid Disodium Salt
EINECS	251-501-5

Quality Control

Our Thymidine-5'-Monophosphate Disodium Salt is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for residual solvents and endotoxins. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
pH (5% Solution)	7.0 - 9.0
Endotoxin (LAL)	<10 EU/mg
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.