Description

3α,6α-Bis(Trimethylsiloxy)-5β-Pregnan-20-One is a key synthetic intermediate in the production of high-value steroid derivatives and active pharmaceutical ingredients (APIs). This compound matters for its role in enabling precise chemical modifications, particularly in the synthesis of complex molecules for therapeutic applications. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on steroid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and novel steroid analogs.
• Fine Chemical Synthesis: Serves as a precursor for manufacturing specialized steroid derivatives with modified biological activity.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial pharmaceutical production.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in steroid analysis.

Basic Information

Product Name	3α,6α-Bis(Trimethylsiloxy)-5β-Pregnan-20-One
CAS No.	33287-43-3
Molecular Formula	C27H50O3Si2
Molecular Weight	478.87 g/mol
Synonyms	3α,6α-Bis(trimethylsilyloxy)-5β-pregnan-20-one; 5β-Pregnan-20-one, 3α,6α-bis(trimethylsiloxy)-; 3α,6α-Bis-O-(trimethylsilyl)-5β-pregnan-20-one; 3α,6α-Di-O-trimethylsilyl-5β-pregnan-20-one; 20-Oxo-5β-pregnane-3α,6α-diyl bis(trimethylsilyl) ether; Pregnane-3α,6α-diol 20-one bis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our 3α,6α-Bis(Trimethylsiloxy)-5β-Pregnan-20-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.