Description

Ethanone, 2,2,2-Trifluoro-1-(2-Pyridinyl)- (9Ci) is a specialized fluorinated pyridine derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoroacetyl group adjacent to the pyridine nitrogen, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors who require sophisticated intermediates for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms contribute to improved lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in transition metal catalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials that incorporate pyridine and fluorinated units.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes that leverage the pyridine moiety for binding interactions.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Pyridinyl)- (9Ci)
CAS No.	33284-17-2
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-pyridinyl)ethanone; 2-(Trifluoroacetyl)pyridine; 1-(Pyridin-2-yl)-2,2,2-trifluoroethanone; α,α,α-Trifluoro-2-pyridyl methyl ketone; 2-Pyridyl trifluoromethyl ketone; TFAP; 2-Trifluoroacetylpyridine
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(2-Pyridinyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.